Department Of Biotechnology

The Department of Biotechnology of Saifia College Bhopal was started in 1996 as one of the first in state of MP under the vocational scheme of UGC New Delhi with BSc Biotechnology Course, followed by MSc in Biotechnology. Since then the department has made significant progress and a large number of students have got their graduate and post graduate degrees with flying colors. All state of the art equipments and facilities for research in applied areas of Biotechnology viz: Animal Biotechnology, Drug Designing and Formulation, Environmental Biotechnology and Biochemistry of very high quality are available in the Department.  The hallmark of the job oriented course has been the very high rate of excellent placements which the students of this college have got in National and International companies both in India and abroad.

The highly qualified faculty members and research scholars of the Department have earned several distinctions in the field of Biotechnology. More than 50 students have got their PhDs in applied areas of Biotechnology. About 10 major research projects from various agencies like UGC, USDA ( PL-480), ICAR, MAPCOST, and MP Biotechnology Council have been successfully completed. More than 150 full research papers have been published by the faculty members and research students of Biotechnology Department Saifia College Bhopal in high impact factor peer reviewed International Journals.

Technical Details of the Department of Biotechnology

Technical Details of Biotechnology  Departmental  Laboratories

There are 3 laboratories including well furnished Animal  Cell & Tissue culture Laboratory, Plant Tissue culture Laboratory and PG laboratory, one animal house, one Lecture Conference hall and one Central Instrumental Laboratory (UGC, New Delhi Sponsored) having all the essential facilities for  high quality research  since last 10 years  in the Department of Biotechnology, Saifia Science College, Bhopal.

List of Equipments Available in Department of Biotechnology, Saifia Science College, Bhopal

SNo.
Name of the Instrument
Quantity
Working Status
Company Name
1.
Microprocessor VIS Spectrophotometer 1 WorkingBio Era Life Sciences, Pune
2.
ELISA Reader 1 WorkingBio Era Life Sciences, Pune
3.
PCR (Peltier Model)1 WorkingBio Era Life Sciences, Pune
4.
Gel Documentation System1 WorkingBio Era Life Sciences, Pune
5.
Western Blotting Assembly Gel Rocker1 WorkingBio Era Life Sciences, Pune
6.
Vertical Electrophoresis Assembly 3 WorkingBio Era Life Sciences, Pune
7.
Horizontal Electrophoresis Assembly 3 WorkingBio Era Life Sciences, Pune
8.
UV Transilluminator1 WorkingJyotiScientfic, Gwalior
9.
CO2Incubator1 WorkingLARK ,Chennai
10.
Laminar Air Flow2 WorkingJyotiScientfic, Gwalior
11.
Revolutionary Micro centrifuge2 WorkingTarsons USA
12.
Revolutionary Table Top High speed Cooling Centrifuge2 WorkingBio Era Life Sciences, Pune Remi
13.
Centrifuge 3 WorkingRemi
14.
Orbital Shaking Incubator 1 WorkingScientech
15.
Trinocular Research Microscope with Image Analyzing Software 1 WorkingQuasmo, India
16.
Digital Trinocular Research Microscope 2 WorkingBio Era Life Sciences, Pune
1.
Microprocessor VIS Spectrophotometer 2 WorkingQuasmo, India
17.
Inverted Tissue Culture Microscope1 WorkingWester Electronic Scientific Works ,Ambala
18.
Microprocessor Spectrophotometer1 WorkingBio Era Life Sciences, Pune
19.
Single Beam UV-Vis Spectrophotometer with Software1 WorkingBio Era Life Sciences, Pune
20.
BOD Incubator1 WorkingION Electronics
21.
Serological Water Bath2 WorkingBio Era Life Sciences, Pune
22.
Double Distillation Unit1 WorkingJyoti Scientific, Gwalior
23.
Triple Distillation Unit 1 Working-
24.
Digital PH Meter1 Working-
25.
Magnetic Stirrer1 WorkingScientech
26.
Soxlet apparatus2 WorkingJyoti Scientific, Gwalior
27.
High Precision Electronic Balance1 WorkingWensarTM (HPB220)
28.
Digital Balance5 WorkingGagles Pvt. Ltd.
29.
Microprocessor Based D.O. Meter1 Working-
30.
Compound Microscopes WorkingMSW and Olampus
31.
Rotary Microtome1 Working-
32.
Tissue Grinder1 WorkingJyoti Scientific, Gwalior
33.
Vacuum Pump1 Working-
34.
Muffle Furnace1 Working-
35.
Autoclave1 WorkingJyoti Scientific, Gwalior

Departmental Library

There are more than 2000 books and large number of journals available in the department of Biotechnology

Details of Journals subscribed by the faculty in the Department of Biotechnology

SNo.
Name of Journal
Title
Vol Since
1.
Everyman’s ScienceKolkata1995
2.
Current ScienceBangalore2000
3.
Journal of Environmental Science and EngineeringNEERI, Nagpur1998
4.
Bioscience Biotechnology Research CommunicationsBhopal2008
5.
Indian Journal of Environmental Health NEERI Nagpur1998

Research Projects Completed By the Department

Details of Projects Completed By the Department of Biotechnology

SNo.
Name of the funding agency
Name of the Scheme
Programme Title
Year of Funding
Duration
Amount Sanctioned
Status: Ongoing/ Completed
1.
MPCOST, BhopalResearch project Effect of histamine releasers on amphibian skin pigmentation and its blockade by drugs with reference to leukoderma1985 3 yearsRs. 1,00,000/-Completed
2.
US Department of AgricultureResearch project Management of productivity and production of fish in sewage pond effluents from urban areas1985 5 yearsRs. 18,00,000/-Completed
3.
MPCOST, BhopalResearch project Pharmacological and Toxicological studies of amphibian and reptilian melanocytes with reference to pigmentary disorders1995 3 yearsRs. 1,08,000/-Completed
4.
UGC, New DelhiResearch project Effects of UV light and background adaptations on amphibian melanophores1996 3 yearsRs. 1,45,000/-Completed
5.
MPCOST, Bhopal Research project Screening of novel Antivitiligo agents from plant extracts using animal melanocytes.2008 3 yearsRs.3,50,000/- Completed
6.
MP Biotechnology Council, Bhopal Research project Molecular studies on Mechanism of Melanolysis using Cell Lines2010 3 yearsRs 5,20, 000/-Completed
7.
MPCOST, Bhopal Research project Ultrastructural studies of amphibian and mammalian melanocytes in culture during the process of induced melanogenesis by certain plant active ingredients2012 2 yearsRs. 4,98,000/- Completed

Publication List of the Department of Biotechnology

COMPLETE LIST OF 150 FULL RESEARCH PAPERS PUBLISHED IN PEER REVIEWED INTERNATIONAL JOURNALS OF HIGH IMPACT FACTOR FROM THE DEPARTMENT OF BIOTECHNOLOGY

  1. Ali SA, Parveen N and Ali AS. (2018). Recent updates on pathogenesis of vitiligo and melanocytes regeneration using herbal extracts. Editors  F. Murid Nobel Laureate In: Herbal Medicines Back to Future, Bentham Science Publishers. (In-Press).
  2. Khan Z and Ali SA. (2018). Oxidative stress-related biomarkers in Parkinson’s disease: A systematic review and meta-analysis. Iranian Journal of Neurology. (Accepted).
  3. Zaidi KU, Ali SA, Ali AS and Naaz I (2018). Natural tyrosinase inhibitors: Role of herbals in the treatment of hyperpigmentary disorders. Mini Reviews in Medicinal Chemistry. (Accepted).
  4. Khan N, Ali SA, Parveen N (2018). On the inhibition of melanogenesis by eugenol from Ocimum sanctum leaves through the downregulation of tyrosinase expression in murine melanoma cells. International Journal of Molecular and Cellular Medicine. (Under Review).
  5. Mahor G and Ali SA (2018). Protective effect of Aloe vera extract on Aluminium induced alteration in serum lipid profile of male albino rat (Rattus norvegicus). Toxicological Report, Elsevier (Under Review).
  6. Parveen N, Ali SA, Ali AS (2018). Insights into the explication of tyrosinase inhibitors with reference to computational studies. Letters in Drug Design and Discovery. (Under Review).
  7. Naaz I and Ali SA (2018). Berberine induced melanogenesis in mouse B16 melanoma cells via upregulation of tyrosinase expression: perspective for the treatment of hypopigmentary disorders. In Vitro Cellular and Developmental Biology-Animal. Springer (Under Review).
  8. Naaz I and Ali SA (2018). Isolation and characterization of bioactive compound berberine in the root extract of Berberis vulgaris for the development of novel skin darkening agent. Journal of Analytical and Pharmaceutical Research. (Accepted)
  9. Ali SA, Parveen N, Ali AS. (2018). Links between the Prophet Muhammad (PBUH) recommended foods and disease management: A review in the light of modern superfoods. International Journal of Health Sciences Pub Med 12(2): 61–69.
  10. Zaidi KU, Ali SA, Ali AS. (2018).Purified Mushroom Tyrosinase Induced Melanogenic Protein Expression in B16F10 Melanocytes: A Quantitative Densitometric Analysis.The Open Medicinal Chemistry Journal. 12,36-47.
  11. Ali SA and Naaz I. (2018). Biochemical aspects of mammalian melanocytes and the emerging role of melanocyte stem cells in dermatological therapies. International Journal of Health Sciences Pub Med, 12(1): 69-76.
  12. Ali SA. (2017). Recent advances in treatment of skin disorders using herbal products. Editorial For Journal of Skin, 1(1):6-7.
  13. Khan N, Ali SA and Parveen N. (2017). The intricacies of vitiligo with reference to recent updates in treatment modalities. European Journal Of Pharmaceutical And Medical Research,5(02), 187-196
  14. Zaidi KU, Ali SA, Ali AS. (2017). Pluripotent Stem Cell Technology: A Promising Remedy for Hypopigmentation Disorders. Journal of Stem Cell Research & Therapeutics 2 (5), 1-4
  15. Parveen N, Zaidi KU, Ali SA andAli AS. (2017). Microarray as high throughput tool for tyrosinase gene expression analysis. MOJ Proteomics & Bioinformatics 6(2): 1-4
  16. Ali SA and Khan Z. (2017). Update on pesticide exposure and Parkinson’s disease: A review. European Journal of Pharmaceutical and Medical Research, 4(8): 224-234.
  17. Zaidi KU, Ali SA and Ali AS, ThawaniV. (2017). Natural Melanogenesis Stimulator a Potential Tool for the Treatment of Hypopigmentation Disease. International Journal of Molecular Biology 2(1): 1-5.
  18. Ali SA, Naaz I, Zaidi KU and Ali AS. (2017). Recent updates on melanocyte biology and the use of promising bioactive compounds for the treatment of hypopigmentary disorders: A review. Mini Reviews in Medicinal Chemistry, 17(9)-785-798.
  19. Zaidi KU, Ali SA and Ali AS (2017). Melanogenic effect of purified mushroom tyrosinase onB16F10 melanocytes: A phase contrast and immunofluorescence microscopic study.Journal of Microscopy and Ultrastructure 5(2): 82-89
  20. Zaidi KU, Ali SA and Ali AS. (2016). Effect of purified mushroom tyrosinase on melanin contentand melanogenic protein expression. Biotechnology Research International. Volume 2016, Article ID 9706214, 8 pages.
  21. JakkalaLK, Ali SA, Choudary RK, Mahor G (2016). Protective role of Aloe veraagainst aluminium induced changes in liver enzymes activity (alt, ast and alp) of albino rats, Rattus norvegicus; World Journal of Pharmacy and Pharmaceutical Sciences, Vol 5(10), 1321-1333.
  22. Jakkala LK and Ali SA. (2016). Aloe vera protects the aluminium induced changes in testicular enzymes activity of albino rats, Rattus norvegicus.World Journal of Pharmacy and Pharmaceutical SciencesVol 5(5) 1091-1104.
  23. JakkalaLK, Ali SA, ChoudaryRK, Mahor G (2016).Aloe veraprotects the aluminium induced changes in liver enzymes activity of albino rats, Rattusnorvegicus,World Journal of Pharmacy and Pharmaceutical Sciences  2016 – Volume 5(6); 1289-1300
  24. Parveen N, Ali SA, Ali AS (2016). Respirocytes: the artificial red blood cells and their role in blood transfusion. International Journal of Advanced Research in Science, Humanities & Engineering.
  25. Zaidi KU, Ali AS and Ali SA. (2015). Purification and characterization of high potential tyrosinase from macrofungi and its appliance in food engineering. Journal of Microbiology, Biotechnology & Food Sciences 5(3): 203-206
  26. Jakkala LK, Ali SA (2016).   Protective role of Alove Vera against Aluminium induced changes in the body weight reduction of albino rats, Rattus norvegicus” Asian Journal of Pharmacology and toxicology, 04(15); 33-38.
  27. Jakkala LK and Ali SA. (2015). Amelioration of the toxic effects of aluminium induced histopathological changes in testis of albino rats by Aloe vera. World Journal of Pharmacy and Pharmaceutical Sciences. Vol 5(5) 806-814.
  28. Mahor G and Ali SA. (2015) An update on the role of medicinal plants in amelioration of aluminium toxicity. BBRC Vol 8 (2) 177-188
  29. Jakkala LK and Ali SA. (2015).Aloe vera protects aluminium induced changes in brain enzyme activity of albino rats, Rattus norvegicus. BBRC Vol 8(2) 197-203
  30. Ali SA, Khan SA, Naaz I and Ali AS. (2015). Adverse health effects of pesticide exposure in workers of a pesticide manufacturing factory BBRC. Vol 8 No.(2) 208-212
  31. Jakkala LK and Ali SA (2015).Aloe vera protects the aluminium induced degenerative changes in liver and kidney of albino rats, Rattus rattus. Journal of Global Biosciences, Volume 4(8)(2015),p3158-3164
  32. Jakkala LK and Ali SA (2015).  Amelioration of the toxic effects of aluminium induced neuro degenerative changes in brain of albino rats by Aloe vera. Journal of Global Biosciences, Vol 4(8),pp:3171-3177
  33. Prasad S, Ali SA, Banerjee P, Joshi J, Sharma U, and Vijh RK. (2015). Population genetic structure of the camel, Camelus dromedarius based on microsatellite loci: Knock-on effect for conservation BBRC Vol.8 No.(2) 153-160
  34. Ali SA, Choudhary RK, Naaz I, Khan N, Sajid M, Galgut J, Miraj M, Jakkala L and Ali AS. (2015). Comparative characterization and scientific validation of certain plant extracts from their biomedical importance. Biosci. Biotech. Res. Comm, 8(1): 57-64.
  35. Ali SA, Choudhary RK, Naaz I and Ali AS. (2015). Understanding the challenges of melanogenesis, key role of bioactive compounds in the treatment of hyperpigmentary disorders. Journal of Pigmentary Disorders, 2(11)
  36. Miraj M and Ali SA. (2015). Body weight responses of carrageenan induced arthritic rats during their treatment with different application of curcumin. Biotech. Res. Comm. 7(2): 163-165.
  37. Ali SA and Naaz I. (2015). Understanding the ultrastructural aspects of berberine induced skin darkening activity in the toad, Bufo melanostictus Journal of Microscopy and Ultrastructure, Elsevier USA, 3(4): 210-219.
  38. Ali SA and Naaz I. (2015). Current challenges in understanding the story of skin pigmentation: Bridging the morpho-anatomical and functional aspects of mammalian melanocytes. In: Muscle Cell and Tissue. Pp 262-285.Kunihiro Sakuma (Ed.) InTech Open House,Europe, USA.ISBN 978-953-51-2156-5, Published: September 2, 2015.
  39. Prasad S, Ali SA, Vijh RK. (2015). Genetic and demographic bottleneck analysis of Malvi Camel breed by Microsatellite markers. Camel Research and Practices (Accepted).
  40. Prasad S, Ali SA, Vijh RK. (2015). Population genetics structure of the Camel (Camelus dromedarius) based on microsatellite loci: knock-on effect for conservation (Accepted).
  41. Prasad S, Ali SA, Vijh RK. (2015). RNA-Seq: A revolutionary tool (Accepted).
  42. Prasad S, Ali SA, Banerjee P, Joshi J, Sharma U, Vijh RK. (2014). Genetic characterization of Malvi Camel using Microsatellite markers. International Journal of Biomedical & Life Sciences, 5(1).
  43. Prasad S, Ali SA, Banerjee P, Joshi J, Sharma U, Vijh RK. (2014). Identification of SNPs and their validation in camel (Camelus dromedarius). IOSR Journal of Agriculture and Veterinary Science (IOSR-JAVS) 7(2):65-70.
  44. Ali SA (2014).The dilemma of quality publication and its benefits in India. Current Science (Indian Academy of Science Bangalore) August 25th107- No.4, 559
  45. Khan N and Ali SA. (2014).HPLC-MS analysis of isoliquiritigenin from the root extract of Glycyrrhiza glabra for developing a novel depigmenting agent. Biotech. Res. Comm. 7(1): 89-93 (2014)
  46. Ali SA, Khan SA, Naaz I and Ali AS. (2014). Adverse health effects of pesticide exposure in workers of a pesticide manufacturing factory of Bhopal Journal of Clinical Toxicology (Under Review).
  47. Choudhary A, Ali AS and Ali SA (2014). Adverse health effects of organophosphate pesticides among occupationally exposed farm sprayers : A case study of Bhopal Madhya Pradesh, India Asian Journal of Biomedical and Pharmaceutical Sciences 4 (35) 29-34.
  48. Ali SA and Naaz I. (2014). Comparative light and electron microscopic analysis of dorsal skin melanophores of Indian toad, Bufo melanostictus. Journal of Microscopy and Ultrastructure, Elsevier USA, 2: 230-235.
  49. Zaidi KU, Ali SA, Ali AS and Naaz I. (2014).Microbial tyrosinase: promising enzyme for pharmaceutical, food bio-processing and environmental industries. Biochemical Research International,USA Vol. 2014 (Article ID-854687,15 page).
  50. Khan N and Ali SA. (2014). Quantitative determination of Eugenol in aqueous extract of Ocimum sanctum by High Performance Thin Layer Chromatography. Journal of Pharmacy Research8(8),1158-1161.
  51. Ali SA, Naaz I and Choudhary RK. (2014). Berberine induced pigment dispersion in Bufo melanostictus melanophores by stimulation of beta-2 adrenergic receptors. Recep. Sign. Transd. (Informa, USA) 34(1):15-20.
  52. Choudhary A, Ali AS and Ali SA. (2014). Organophosphate pesticides exposure induces neurological disorders in the farm sprayers of Bhopal, Madhya Pradesh. Biotech. Res. Comm. 7(1) 58-61
  53. Zaidi KU, Ali AS and Ali SA. (2014). Purification and Characterization of Melanogenic Enzyme Tyrosinase from Button Mushroom. Enzyme Research, Volume 2014 (2014), Article ID 120739, 6 pages.
  54. Choudhary A, Ali AS and Ali SA. (2013). Short and long term exposure dependent assessment of organophosphate pesticides in farm sprayers of Bhopal. International Journal of Toxicology. (Communicated)
  55. Choudhary A, Ali AS and Ali SA. (2013). Assessment of certain biochemical responses of organophosphate pesticide sprayers of Bhopal. Interdisciplinary Toxicology. (Communicated).
  56. Sajid M and Ali SA. (2013).HPTLC analysis of piperine from Piper nigrum, a possible candidate for vitiligo treatment. Biotech. Res. Comm. 6(1): 107-109.
  57. Zaidi KU, Manil A, Ali AS and Ali SA. (2013).Evaluation of tyrosinase producing endophytic fungi from Calotropis gigantea, Azadirachta indica, Ocimum tenuiflorum and Lantana camara. Annual Review & Research in Biology 3(4): 389-396
  58. Singh A, Vajpayee M, Ali SA, Chauhan NK. (2013). Loss of RORγt DNA binding activity inhibits IL-17 expression in HIV-1 infected Indian individuals.Viral Immunol. USA 26(1): 60-70.
  59. Singh A, Vajpayee M, Ali SA, Chauhan NK. (2013). Cellular interplay among Th17, Th1 and Treg cells in HIV-1 subtype C infection. Journal of Medical Virology (John Wiley) DOI 10.01002/jmv.23810.
  60. Salim S, Ali AS and Ali SA. (2013). 5-HT receptors subtypes as key regulators in causing pigment dispersion within the melanophores of mossambicus. Comp. Biochem. Physiology. Elsevier USA (Part B) 164(2): 117-23.
  61. Ali SA, Salim S, Sahni T, Peter J and Ali AS.(2012c). 5- HT receptors as novel targets for optimizing skin pigmentary responses in dorsal skin skin melanophores of frog Hoplobatrachus tigerinus. British Journal of Pharmacology, K. The British Pharmacological Society165(5): 1515–1525 John Wiley UK
  62. Ali SA, Choudhary RK and Jakkala LK. (2012). Quantitative estimation of Aloin from Aloe vera leaf extracts by High Performance Thin Layer Chromatography. Biotech. Res. Comm. 5(2): 206-209.
  63. Salim S and Ali SA. (2012). Melanophores : The smooth Muscle Cells in Disguise In: Current Basic and Pathological Approaches to the Function of Muscle Cells and Tissues – From Molecules to Humans.Pp 133-158.Harou Sugi (Ed.) InTech Open House. ISBN 980-953-307-029-7 Europe, USA
  64. Singh A, Vajpayee M, Ali SA, K Mojumdar and Chauhan NK. (2012). HIV-1 diseases progression associated with loss of Th17 cells in subtype ‘C’ infection, Cytokine Elsevier USA60(1): 55–63,
  65. Salim S, Ali SA and Ali AS. (2012a).The Peripheral bearing of Serotonergic receptors and their cross interaction: a key mien in Vertebrate Skin Pigmentation. IISTE, USA.
  66. Salim S, Ali AS and Ali SA. (2012b). Auto-regulatory role of novel histamine H3 Like receptors (H3R) and subsequent modulation of adrenergic induced aggregation in the pigmentary responses of Oreochromis mossambicus. Pharmacologia   UK Science Reuters 3 (8): 325-335.
  67. Salim S, Ali AS and Ali SA. (2012c).On the role of Histaminergic receptors as regulators of pigmentary responses in mossambicus melanophores. Journ. Recep. Sign. Transd USA32(6): 314-20.
  68. Vajpayee M, Singh A, Ali SA, Kumar N, and Singh R. (2012).Immunodynamics of Th17 cells in HIV-1 subtype C infection. BMC Infectious Disease Suppl., May 4 2012, DOI 10.1186/1471-2334-12-S-03.
  69. Ali SA, Galgut JM and Choudhary RK. (2012). On the novel action of melanolysis by leaf extract of Aloe vera and its active ingredient aloin, the potent depigmenting agent. Planta Medica UK (Thieme) 78, 1-5
  70. Chaudhari SA, Peter J, Galgut JM and Ali SA. (2012). Melanin Inhibitory and melanin stimulatory effects of extracts of Chlorophytum tuberosum and Chlorophytum borivilianum on isolated fish scale melanophores. African Journal of Pharmacy and Pharmacological Research,6 (12): 919-923.
  71. Galgut J.M. and Ali SA. (2012). Hesperidin induced melanophoreaggregatory responses in tadpole of Bufo melanostictus via α-adrenoceptors. Pharmacologia 3(10): 519-524 (DOI 10.5567), Science Reuters (UK).
  72. Ali SA and Meitei KV (2012). Withania somnifera root extracts induce skin darkening in the wall lizard melanophores via stimulation of cholinergic receptors. Natural Product Research (UK), 26(17): 1645–1648.
  73. Meitei KV and Ali SA. (2012). Fig leaf extract and its bioactive compound psoraleninduces skin darkening effect in reptilian melanophores via cholinergic receptor stimulation. In Vitro Cellular & Developmental Biology – Animal. 48(6):335-33: Springer USA
  74. Ali SA and Meitei KV (2012). Nigella sativa seed extract and its bioactive compound thymoquinone the new melanogens causing hyperpigmentation in the wall lizard melanophores. Journal of Pharmacy and Pharmacology, Great Britain Society UK (Wiley – Blackwell ) IF 3.0  63-741- 746
  75. Khaliq R, Ali SA, Zafar T, Farooq M and Bilal A. (2012). Effect of pollution on the fish diversity of Wularlake of Kashmir. Biotech. Res. Comm. 5(2): 158-161.
  76. Khaliq R, Ali SA, Zafar T, Farooq M and Bilal A. (2012). Physiochemical status of Wular Lake in Kashmir. Journal of Chemical, Biological and Physical Sciences. 3(1) 631-636
  77. Ali SA, Salim S, Ali AS, Peter J. (2011). In vitro analysis on the effects of UV-B radiation on the dorsal skin melanophores of Indian Bull frog Haplobatrachus tigrinus. International Journal of Pharma and Biosciences. 2(4):B158-B173.
  78. Ali SA and KV Meitei (2011) On the action and mechanism of withaferin-A from Withania somnifera a novel and potent melanin dispersing agent in frog melanophores. Journal of Receptors & Cell Transduction USA, 31(5): 367-373.(IF: 1.894)
  79. Sultan and Ali SA. (2011) Psoralea corylifolia extracts stimulate cholinergic like psoralen receptors of tadpole tail melanophores leading to skin darkening. Journal of Receptors & Cell Transduction USA. 31(1):39-44.
  80. Salim S and Ali SA. (2011) Vertebrate Melanophores as potential model for drug discovery and development: A Review. Mol. Biol. Letters UK. 16(1) :162-200
  81. Ali SA, Sultan, Galgut JM, Sharma R., Meitei KV and Ali AS. (2011): In vitro responses of fish melanophores to lyophilized extracts of Psoraleacorylifolia seed sand  pure psoralen Accepted in  Pharmaceutical Biology.USA  (doi:10.3109/ 10799893.2010.508164)
  82. Salim S, Ali AS and Ali SA. (2011) Insights into the physio-modulatory role of histaminergic receptors in vertebrate skin pigmentation: Journal of Receptors and Signal transduction, USA. 31(2): 121-31.
  83. Peter J, Meitei KV, Ali AS and Ali SA. (2011) Effects of histaminergic compounds on the melanophore responses of the wall lizard, Hemidactylus flaviviridis. Current Science101(2): 226-229.
  84. Ali SA, Ali AS & Peter J (2011) Effect of Ultraviolet – B Radiation on the Skin Melanophores of Indian bullfrog Hoplobatrachus tigerinus.BioScience. (USA), 2(4): 158-173
  85. Galgut JM and Ali SA. (2011) Effect and mechanism of action of resveratrol: a novel melanolytic compound from the peanut skin of Arachis hypogaea. Journal of Receptors and Signal Transduction. 31 (5):374–384.USA
  86. Galgut JM, Ali SA and Peter J. (2011) Estimation of resveratrol in Arachis hypogaea fruit skin extracts by High-Performance Thin-Layer Chromatography. Bioscience and Biotechnology Research Communication. 4 (1):37-40.
  87. Galgut JM and Ali SA. (2011) Hesperidin induced melanophore aggregatory responses in tadpole of Bufo melanostictus via α- adrenoceptors. PharmacologiaUK. 3(10):519-524]
  88. Sajid M and Ali SA. (2011). Mediation of cholino-piperine like receptors by extracts of Piper nigrum induces melanin dispersion in Rana tigerina tadpole melanophores. J. Receptors & Signal Transduction, USA, 31 (4) :286-290(IF: 1.894)
  89. Singh RK, Ali SA, Nath P and Sane VA (2011). Activation of ethylene-responsive p-hydroxyphenylpyruvatedioxygenase leads to increased tocopherol levels during ripening of mango. Journal of Experimental Biology, 6; 1-11.
  90. Ali AS, Mitra J and Ali SA. (2011). Biochemical markers for toxicological assessment A review Biochemical markers for toxicological assessment: Delhi Publishing Company: 117-131.
  91. Singh RK, Sane VA, Misra A, Ali SA, Nath P (2010): Members of Alcohol dehydrogenase gene family in mango express differentially during ripening.Phytochemistry, Elsevier USA71:1485–1494.
  92. Shaik NA, Jilani SP, Ali SA, Imran A and Rao DK (2010).Increased frequency of micronuclei in diabetes mellitus patients using pioglitazone and glimepiride in combination.Food and Chemical Toxicology.Elsevier,USA48(12): 3432-3435.
  93. Awasthi D, Meitei KV, Mishra R. and Ali SA. (2009) Validation of harvesting period for obtaining optimum concentrations of withanoloidesfrom Withaniasomnifera at different phenological stages of plant Indian J. Tropical Biodiversity.17(2):129 -132.
  94. Yadav S and Ali SA. (2009). Cadmium hazards to Birds: A synoptic view. Hunt. 4(2): 35-41.
  95. Yadav S, Ali AS &Ali SA. (2009). Vitamin A ameliorates toxic effects of cadmium in domestic fowl. Indian Journal of Poultry Science ICAR Govt of India New Delhi .44(3): 402-404
  96. Ali AS., Khan I and Ali SA. (2009). Bioremediation of contaminated soils using In Hand book of Agriculture Biotechnology, Ed DK Maheshwari International Publishers New Delhi
  97. Parveen A, Ali AS and Ali SA. (2009). Role of shore line macrophytes in management and conservation of a tropical lake. Biotech. Res. Comm. 2 (2): 195-199
  98. Singh A and Ali SA. (2009). TH 17 Cells: New Members of T Helper (TH) Lymphocyte family Biotech. Res.Comm, 2(2): 133-138
  99. Ali SA and Metei KV. (2009). Identification and quantification of thymoquinione from the seeds of Nigella sativa Biotech.Res.Comm. 2(2): 250-251
  100. Pandey, Ali AS., Sajid M and Ali SA. (2008). Certain Biochemical studies on the Leaves of Medicinal Plant, Eclipta alba. Biotech Research Comm. 1 (1):59-63.
  101. Ali SA, Malik S, Meitei KV, Sultan T, Sajid M , Ali AS and Ovais  (2008) Pharmacological effects of Lead Nitrate, Adrenaline and Potassium on isolated fish melanophores. Biosc. Biotech. Res. Comm. 1(1): 64-69.
  102. Ali SA, Saxena M, Meitei KV, Sajid M and Ali AS. (2008) Biochemical studies of crude extracts of roots and leaves of Withania somnifera. Biotech Res Comm, 1(2):168-172.
  103. Awasthi D, Nigam RK and Ali SA. (2008) Secondary metabolite enhancement through elicitation of micro propagated plants of Ashwagandha (Withania somnifera L. Dunal) Biotech Res Comm, 1(2):173-180.
  104. Ali AS, Khan I. and Ali SA. (2007) Toxicological Monitoring using Earthworms. In: Toxicology & Science of Poisons, Aavishkar Publishers Jaipur, 167-186.
  105. Khan I, Ali AS and Ali SA. (2007) Biomass and behavioral responses of earthworm terrestris to Copper Chloride.Iranian Journal of Toxicology 2 :64-71
  106. Ahmed MS, Ali SA, Ali AS and Chaubey KK. (2006). Epidemiological and etiological study of oral sub mucous fibrosis among gutkha chewers of Patna. J. Indian Society of Pedodontics and Preventive Dentistry. 24(2): 84-89.
  107. Ali SA et al. (2006) Friendly Earthworms. Science Reporter, CSIRGovt of India New Delhi43(1): 28-30.
  108. Ahmed MS, Ali SA, Ali AS. AndChaubey KK. (2006). Comparative severity of oral sub mucous Fibrosis in gutkha and other areca nut product Chewers Priory Dentistry On Line 1-11.
  109. Yadav S and Ali SA. (2005). Role of vitamin A in the regulation of some aspects of cadmium toxicity in Clarias batrachus. Biotech. Res.Asia.3 (2): 371-374.
  110. Ahmad MS, Ali SA, and Ali AS. (2005). Site distribution of oral carcinoma reported cases in some tobacco- lime mixture Biotech. Res. Asia. 3(2):329-334.
  111. Ahmed MS, Ali SA and Ali AS. (2004) Understanding the pathological nature of oral plaque and its role in dental carries. Biosci. Biotech. Res. Asia. 02 (1):25-32.
  112. Khan MI, Baig MA and Ali SA. (2004). Immobilization of enzyme trypsin by alginate gel through encapsulation. Indian J. Applied and Pure Biology. 19 (3):383-388.
  113. Ali SA, Ali AS, Ali SN and Jain R. (2004). Effects of ultraviolet-C radiation on isolated fish scale melanophores. Indian Journal of Radio & Space Physics. CSIR Govt of India New Delhi .33:58-60.
  114. Ali SA. (2000). Monitoring and evaluation of domestic waste water for fish culture. Aquaculture Research Needs For the Year 2000 AD, Oxford University Press UK US Department of Agriculture & ICAR New Delhi Publication  87-99
  115. Ali SA. (1999) Science in Indian Universities: Problems and solutions,Current Science (Indian Academy of Sciences Bangalore)  24:5-6.
  116. Ali SA, Peter J, Ali AS. (1998) Histamine receptors in the skin melanophores of Indian Bull frog, Ranatigerina. Biochem. Physiol A. Elsevier: 121:229-234.
  117. Khan SA, Ali SA, Ohri B. (1997). Sex related differences in blood glucose levels of human subjects. J. Chem. 13(2): 185-186.
  118. Ali SA and Raju H. (1997) Histopathological examination of gills of Cyprinus carpio cultured in Domestic Waste Oxidation Ponds. J. Environ. Health, NEERIGovt of India. 12(3): 143-146
  119. Peter J, Ali AS, Ali SA. (1996). Effect of histaminergic drugs on the integumentalmelanophores of adult Bufomelanosticus. Ind J. Expt. Biol CSIR Govt of India New Delhi 34:427-430.
  120. Peter J, Ali AS and Ali SA. (1996). Ionic regulation of toad skin melanophores. Ind J. Zool Spectrum. 6(2): 47-50.
  121. Peter J, Ali SA, Ali AS.(1996). Effect of certain phenolic compounds on the isolated scale melanophores of fish, punctatus. XVIth Intl Pigment Cell Conf.Anahiem, California,USA In: Pigment Cell Res. Suppl. 5, 68, 71.
  122. Ali SA, Peter J, Ali AS. (1996). The presence of histaminergic components in the melanophore responses of lower vertebrates. XVIthInt Pigment Cell Conf.Anahiem, California,USA In: Pigment Cell Res. Suppl. 5, 64, 171.
  123. Ali SA, Khan SA, Ali AS. (1995). Enforcement of environmental laws and regulations. Environmental Conservation (Cambridge University Press UK), 22(01): 77-78
  124. Ali SA et al. (1995). On the presence of carbohydrates in the ovary of Indian field rat. Nesociabandicoota. Ind J. Zool Spectrum. 6:19-24.
  125. Ali SA et al. (1995). Role of cholinergic receptors in melanophore responses of amphibians. Acta Biol. Hungarica. 46(1): 61-73.
  126. Ali SA, Khare S., Khan MA., Ali AS. (1993) Prospects of culture of fresh water prawns in waste water ponds, In: Proceedings Nat. Sem. Aquatic Biology, University of Kerala,Thiruvanthapurampp 27-32.
  127. Ali SA.,Peter J, Ali AS (1993) Effects of histaminergic drugs on tail melanophores of tadpole, Bufomelanosticus, J. Exptl. Biol,CSIRGovt of India New  DelhiVol. 31. pp 440-442.
  128. Khan AS, Ohri BS, Ali SA. (1993) Lipid profile as a tool to evaluate coronary heart disease risk. J. Chem. Vol. 9. pp 162-164.
  129. Ali SA, Khan S.A. (1993) Assessment of certain haematological factors in pesticide exposed factory workers, Environ. Contam. Toxicol, Springer USA, Vol. 51, No. 5, pp 750-747
  130. Ali SA, Peter J., Ali AS, H. Raju(1992) Histopathological evaluation of gills of carps cultured in domestic waste oxidation ponds. Ind J. Zool Spectrum, Vol 4, No. 2, pp. 23-27.
  131. Ali SA, Khan S. (1992) Status of suspended and dissolved solids in tropical oxidation ponds and their removal through fish culture, Orient J. Chem,Vol 8, 352-355.
  132. Ali SA, Peter J., Ali AS, (1991) Effects of alkaline earth ions on integumentalmelanophores of Indian frog,Ranatigerina. J. Zool. SpectrumVol 2, pp 15-19.
  133. Ali SA, Khan S and Ohri BS (1991) Diagnostic application of ELISA in thyroid function test in developing countries, Ind J. Zool SpectrumVol 2-1, pp 43-45
  134. Ali SA, Aleem I. (1991) On the presence of Streptococci in Narmada river at Hoshangabad, Ind J. Zool Spectrum Vol 2, 35-37
  135. Ali SA. (1988) Final Tech. Report USDA/ PL- 480.USAProject No.In: 623, FG In: AES, 208, pp1-200
  136. Ali SA. (1987)  IIIrd Ann. Tech Res. Proj. Report USDA-PL-480 American Project No, FG In: In AES 208, pp. 1-96.
  137. Ali SA. et al., (1987) Seasonal studies on the biomass of waste stabilization ponds of Bhopal, J. Zool. Vol. 150, 43-47.
  138. Ali SA. (1986) First Annual Tech Res. Report, USDA PL- 480 Intl. Res. Project Management of     productivity and production of fish in sewage pond effluents.  FG In: 623 In:AES/208, pp. 1-80
  139. Ali SA. (1986) BylemFiarasemiertelnegoGazu. W. Bhopal. Polish Journal of Environmental Science. AuraPoland 3, No. 159,pp. 25-26
  140. Ali AS, Ali SA, Belsare DK.(1986) Phenyl mercury acetate induced hypothyroid  condition of  pigeon, Columba   livia. J. Applied Biol.Vol. l, pp. 29-32.
  141. Ali SA. (1986) Sec. Annual Tech. Report, FG IN: 623, USDA PL-480 Res. Project pp 1-186.
  142. Ali SA. (1986) Characterization of histaminergic receptors on isolated fish melanophores. Invest. Dermatol. Vol 87, No. 3, 29-31.
  143. Ali SA, Ali A.S. (1985) The anticholinesterase activity of dichlorovos (DDVP) in isolated melanophores of Channa punctatus. J. Chem., Vol.1 (1), pp. 41-43.
  144. Ali SA, Ali AS Ovais M Belsare DK. (1985).Invitro effect of cyclic AMP on teleost melanophores. Acad. Science Letters, Vol. 193, pp. 294-297
  145. Ovais, M. and Ali SA. (1984) Effect of autonomic drugs on the melanophores of wall lizard, Hemidactylusflaviridis. Current Science, Vol. 53, No. 6, pp. 303-306
  146. Ali, AS Ali SA, Belsare, DK  (1984) Effect of phenyl mercury acetate on ovary and crop of pigeon, Columba livia, J. Zool. Vol. 12, No. 2, pp. 40-44.
  147. Ali SA (1983) Physiology and pharmacology of melanophores of teleostean fish Channa punctatus. D thesis, Barkatullah University, Bhopal. pp. 1-203. ( BARC-DAE Govt of India, National Fellowship Programme)
  148. Ali SA, Sabnis PB. (1979) Somehistopathological changes observed in the testes of rat, Rattus rattus. J. Zool, Vol. 7, No. 2.,pp 37-40.
  149. Ali SA, Ovais, M. (1979) Ionic regulation of melanophore activity in teleost Channa punctatus. J. Zool, Vol. 3. pp. 60-66.
  150. Ali SA (1978) Effect of vasectomy on the physiology of testicular function of rat,Rattusrattus, MSc Dissertation, Nagpur University, Nagpur , pp. 1-45.

Patent Filed By Biotechnology Dept Scholars & Faculty

Filed a patent entitled:  Screening method for detecting an active melanolytic agent.

Patent No. :2895/MUM/2012   National Research Development Corporation New Delhi  Ref No.: IPR/11085-L/2011

Patent Holders  : Dr Sharique Ali and  Dr. Jyoti Galgut

Postgraduate Department of Biotechnology Saifia Science College Bhopal

List of PhD students of Biotechnology Department

SNo.
Name of Scholar
Date of Registration/Year of award
Name of Supervisor/Co-Supervisor with address
1.
Dr Tariq ZafarAwarded 1985Dr. Sharique A. Ali, Saifia Science College, Bhopal
2.
Dr. Shamim A. KhanAwarded 1989Dr. Sharique A. Ali, Saifia Science College, Bhopal
3.
Dr. Satyendra KhareAwarded 1989Dr. Sharique A. Ali, Saifia Science College, Bhopal
4.
Dr. M. QureshiAwarded 1991Dr. Sharique A. Ali, Saifia Science College, Bhopal
5.
Dr. M.H. RajuAwarded 1992Dr. Sharique A. Ali, Saifia Science College, Bhopal
6.
Dr. Ishrat Aleem Awarded 1992Dr. Sharique A. Ali (Co-Guide) , Saifia Science College, Bhopal
7.
Dr. Shoeb A. KhanAwarded 1993Dr. Sharique A. Ali, Saifia Science College, Bhopal
8.
Dr. Jaya PeterAwarded 1994Dr. Sharique A. Ali (Co-Guide) , Saifia Science College, Bhopal
9.
Dr. Kiran SharmaAwarded 1996Dr. Sharique A. Ali, Saifia Science College, Bhopal
10.
Dr A. Halim KhanAwarded 1998Dr. Sharique A. Ali, Saifia Science College, Bhopal
11.
Dr. S. MalikAwarded 2002Dr. Sharique A. Ali, Saifia Science College, Bhopal
12.
Dr. Ravi JainAwarded 2004Dr. Sharique A. Ali, Saifia Science College, Bhopal
13.
Dr. Sangeeta Choudhary Awarded 2006Dr. Sharique A. Ali, Saifia Science College, Bhopal
14.
Awarded 2005Awarded 2004Dr. Sharique A. Ali (Co-Guide) , Saifia Science College, Bhopal
15.
Dr. Sunita YadavAwarded 2009Dr. Sharique A. Ali, Saifia Science College, Bhopal
16.
 Dr. Deepesh Awasthi Awarded 2010 Dr. Sharique A. Ali, Saifia Science College, Bhopal
17.
Dr. Raj SharmaAwarded 2010Dr. Sharique A. Ali, Saifia Science College, Bhopal
18.
Dr. Meena Iqbal Awarded 2010Dr. Sharique A. Ali, Saifia Science College, Bhopal
19.
Dr. K.V. Meitei Awarded 2011Dr. Sharique A. Ali, Saifia Science College, Bhopal
20.
Dr. Rajesh Kumar Singh 18-11-2008, (Awarded 2013)Dr. Sharique A. Ali, Saifia Science College, Bhopal
21.
Dr. Mohd.Sajid26-10- 2006 (Awarded 2013)Dr. Sharique A. Ali, Saifia Science College, Bhopal
22.
Dr. Meena Swami Awarded 2014Dr. Sharique A. Ali, Saifia Science College, Bhopal
23.
Dr. Tahira Sultan 26-06-2006 (Awarded 2014)Dr. Sharique A. Ali, Saifia Science College, Bhopal
24.
Dr. Saima Salim Awarded 2014Dr. Sharique A. Ali (Co-Guide) , Saifia Science College, Bhopal

List of Fellowship awardees of Biotechnology Department

List of Ph.D. Students of Department of Biotechnology , Saifia College of Science, Awarded National Fellowships

SNo.
Name of Research Fellow
Supervisor
Area of Research
Funding Agency
1.
Ms. Rumysa KhaliqDr.Sharique A. Ali (Co-guide)ZoologyMANF(UGC, New Delhi)
2.
Mrs. Nargis KhanDr.Sharique A. AliBiotechnologyMANF(UGC, New Delhi)
3.
Ms. Ishrat NaazDr.Sharique A. AliBiotechnologyMANF(UGC, New Delhi)
4.
Mr. GajendraMohorDr.Sharique A. AliBiotechnologyMANF(UGC, New Delhi)
5.
Ms. Naima ParveenDr. Sharique A.Ali (Co-guide)BiotechnologyMANF(UGC, New Delhi)

Placement Record of the Department of Biotechnology

SNo.
Name of Students
Placement
1.
Dr Tariq ZafarVice Chancellor MP Bhoj Unversity, Bhopal
2.
Dr. Shamim A. KhanScientist Water Department, Saudi Arabia
3.
Dr. Satyendra KharePrincipal Scope College, Bhopal
4.
Dr. M. QureshiScientist MP Pollution Control Board, Bhopal
5.
Dr. Ishrat AleemSerior Scientist MAPCOST, Bhopal
6.
Dr. M.H.Raju Asst. Professor. Govt College, Guntur AP
7.
Dr. Shoeb A. KhanBiochemist JN Hospital Govt of MP Bhopal
8.
Dr. Jaya PeterAss. Professor, RKDF University, Bhopal
9.
Dr. Kiran SharmaSenior Lecturer Govt of MP Bhopal
10.
Dr A. Halim KhanProf. of Zoology Saifia College, Bhopal
11.
Dr. S.V. SindhuAsst. Prof. University of kerala
12.
Dr. S. MalikAsst. Prof. University of New Delhi
13.
Dr. Ravi Jain Asst. Prof. SATI Vidisha, M.P.
14.
Dr. Sami AhamadProf. King Saud, University KSA
15.
Dr. A.K.BadayaScientist ICAR Jhabua
16.
 Dr. S. Choudhary Asst. Prof. Govt College Pune MS
17.
Dr. Asma ParveenEnvironmentalist, Bhopal (M.P.)
18.
Dr. Sunita Yadav Asst. Prof. Satya Sai College, Bhopal
19.
Dr. Neelu Qayyumi Asst. Prof. Extol College, Bhopal
20.
Dr. Deepesh Awasthi Scientist MP Forest Produce Govt of MP
21.
Dr. Raj SharmaAsst. Prof. Govt Medical College, Bilaspur, CG
22.
Dr. Meena Iqbal Editor BBRC, Bhopal
23.
Dr. Vibha Kackar Res Fellow NB AGR Karnal
24.
Dr. K.V.Meitel Asst. Prof. Jyoti Womens University, Jaipur
25.
Dr. Tarandeep Kaur Director, Udaan NGO, Bhopal
26.
Dr. Rajesh Singh Post Doc Fellow USDA Maryland, USA
27.
Dr. Mohd. Sajid HOD, Biotechnology Bonnifi College, Bhopal
28.
Dr. Meena Swamy HOD, Zoology Govt. PG College, Chhindwara
29.
Dr. Sameena Zafar Scientist TTTI, Bhopal
30.
Dr. Tahira Sultan Scientist Riyad Univesity Riyad ,KSA
31.
Dr. Priyanka Mishra Res Fellow NB AGR Karnal
32.
Dr. Anjali Choudhary HOD, Biotechnology, Career College, Bhopal
33.
Dr. J.M.Galgut Scientist Qatar University,Qatar
34.
Dr. Saima Salim Post Doc Philadelphia, USA
35.
Dr. Alpana Singh Post Doc AIIMS New Delhi
36.
Dr. Rumysa Khalid SRF-MANF
37.
Mrs. S. Prasad Res Fellow, NB AGR Karnal
38.
Dr. Kamal Zaidi Res Scientist, Peoples University, Bhopal
39.
Dr. Laxman Kumar Director Macrocare Ltd. Hyderabad
40.
Dr. M. Miraj Director, AIHMS, New Delhi
39.
Dr. Laxman Kumar Director Macrocare Ltd. Hyderabad
40.
Dr. M. Miraj Director, AIHMS, New Delhi
41.
Mr. RK.Choudhary Asst. Prof. Biotechnology, Shashib Bhopal
42.
Ms. Nargis Khan MAN Fellow UGC New Delhi
43.
Ms. Ishrat Naaz MAN Fellow UGC New Delhi

About Faculty Members